Gavin Conferences is going to host the International Microfluidics Conference on 26th-27th, May 2020 in Rome, Italy.
Theme: Microfluidic Research Trends and Techniques. Professors, Scientists, researchers related to Microfluidics need to the attend and share the importance of Microfluidics which is an emerging subject.
Microfluidics is the technology of fluid manipulation in channels with dimensions of tens of micrometers it has emerged in recent years as a distinct new area of research thanks to its application in many diverse fields, such as chemistry, biology, medicine, and physical sciences.
A strong motivation in microfluidic research comes from the development of lab-on-chip (LOC) devices, which are expected to bring a revolution in the field of chemistry and biology as integrated circuits did in computation capabilities.
LOCs are microsystems capable of integrating entire biological or chemical laboratories in a single chip, thanks to the integration of microfluidic channels and active or passive components, such as filters, valves, mixers, and many others. The main advantage of LOCs can be found in their ability to manipulate small amounts of fluids. This leads to the possibility of performing analysis with a very limited quantity of samples, thus making most bioanalysis very little invasive and feasible in unspecialized point-of-care centers.
Importance of Microfluidics: -
Microfluidics deals with small liquid volumes, the technology may enable cost-efficient, ultra-high-throughput assays in fields like biology and drug discovery. Many groups are also working on microfluidic devices for point-of-care diagnostics and also in the field of therapeutics (e.g., drug delivery). In addition to making present experimental techniques efficient, microfluidics can be used in new types of experiments. Research on Microfluidics has been conducted since decades in academia, the market potential is only beginning to be explored.
Topics of Microfluidics and Case studies and applications in Medical Research
- Point-of-care diagnostics
- Droplet microfluidics
- Isolation and analysis of CTCs
- 3D printing of microfluidic devices
- Single-cell analysis
POCT is a medical diagnostic testing performed outside the clinical laboratory in close to where the patient is receiving care. It’s performed by non-laboratory personnel and results used for clinical decision making.
Organs On Chips
Organs-on-chips are plastic micro devices the size of a USB-stay with micro-channels and little chambers that are loaded with fluid. The device contains various human cell sorts which are refined in an innovatively controlled microenvironment that misleadingly mimics parts of the human body like morphology, development, movement, flow, stream, electrical stimuli and liquid gradients. The subsequent device mimics human organ functions and can be utilized utilized in biomedical phenomena.
Droplet-based microfluidics or computerized microfluidics is a subclass of microfluidic devices, wherein droplets are created utilizing active or passive techniques. The active strategy for age of droplets includes the utilization of an outer factor, for example, an electric field for droplet generation. Two procedures that fall in this category are electrophoresis (DEP) and electro wetting on dielectric (EWOD). In passive strategies, the droplet generation relies upon the geometry and measurements of the device. T-intersection and stream centering strategies are cases of passive techniques utilized for generation of droplets.
Micro-fabrication is the process of fabricating miniature structures of micrometer scales and smaller. Historically, the most punctual micro-fabrication forms were utilized for coordinated circuit fabrication, otherwise called "semiconductor assembling" or "semiconductor device manufacture".
Isolation and analysis of CTCs
Isolation and analysis of cancer cells from body fluids have huge significant in diagnosis and treatment of tumors. Circling tumor cells (CTCs) are cancer cells flowing in the fringe blood or spreading in the peripheral blood veins, which is an early step in the cascade of events proceeding to cancer metastasis.
Methods of Isolation and Analysis
Isolation Based on Physical Properties
Genetic Analysis of CTCs
Protein and Functional Assays of CTCs
3D printing of microfluidic devices
3D printing can possibly have potential to change the field of microfluidics. The ability to manufacture an entire microfluidic device in single step from a computer model has obvious attractions, however it is the capacity to create three dimensional structures that will give new microfluidic capability that is challenging, if not difficult to make with existing approaches.